4 edition of Pulmonary surfactant found in the catalog.
Includes bibliographical references and index.
|Statement||editor, Jacques R. Bourbon.|
|Contributions||Bourbon, Jacques R.|
|LC Classifications||QP752.P84 P853 1991|
|The Physical Object|
|Pagination||438 p. :|
|Number of Pages||438|
|LC Control Number||90015117|
Surfactant Science: Principles and Practice A free eBook linked to the apps in Practical Surfactants And, by popular request, for those who prefer to sit down and read a real hardback book, you can purchase a copy from DEStech Publications. Everything I've learned whilst developing Practical Surfactants and formulating in the real world is brought together in my book Surfactant . Summary This book represents a comprehensive update on pulmonary surfactant by merging classical knowledge with new information. Topics include surfactant secretion and alveolar processing and recycling; physical bases and different theoretical models of the physiological mechanism for pulmonary surfactant action; recent findings on surfactant-like material in .
Joseph L. Alcorn, in Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease, Abstract. Surfactant is the lipid:protein complex that coats the alveolar surface and greatly reduces surface tension, allowing for efficient inspiration. Surfactant is produced exclusively by alveolar type II epithelial cells and stored in specialized organelles called lamellar bodies (LBs) . "delves into the depths of the biology of pulmonary surfactant in respiratory diseases. The editor's intent to combine current observations regarding the biochemistry of pulmonary surfactants and the biophysics of surface tension phenomena is well-executed in this book." -Doody's ReviewsPrice: $
Genre/Form: Surfactant-System: Additional Physical Format: Online version: Pulmonary surfactant. Amsterdam ; New York: Elsevier, (OCoLC) Infantile respiratory distress syndrome (IRDS), also called respiratory distress syndrome of newborn, or increasingly surfactant deficiency disorder (SDD), and previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of pulmonary surfactant production and structural immaturity in the lty: Pediatrics, obstetrics.
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This item: Pulmonary Surfactant: Biochemical, Functional, Regulatory, and Clinical Concepts. Set up a giveaway. Get fast, free delivery with Amazon Prime. Prime members enjoy FREE Two-Day Delivery and exclusive access to music, movies, TV Cited by: Pulmonary Surfactant System 1st Edition by Cosmi (Author) ISBN ISBN Why is ISBN important.
ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition of a book. The 13 Author: Cosmi. Since the first edition of this book was published inthere has been a spectacular development in both basic research on the pulmonary surfactant system and the clinical use of surfactant for treatment of lung diseases hence the addition of the subtitle indicating the expansion of knowledge in the field and the expanded information Cited by: Genre/Form: Surfactant-System: Additional Physical Format: Online version: Pulmonary surfactant.
Amsterdam ; New York: Elsevier ; New York, NY, USA: Sole. Pulmonary Pulmonary surfactant book is composed of approximately 90% lipids and 10% proteins. Type II pneumocytes secrete surfactant, and it gets metabolized by macrophages.
The proteins found in surfactant play a diverse range of roles, many of which are the topic of : Benjamin D. Seadler, Sandeep Sharma. The pulmonary surfactant system. Pulmonary surfactant is a complex mixture of phospholipids (PL), neutral lipids [particularly cholesterol (Chol)], and proteins.
The PL are assembled in the endoplasmic reticulum and the Golgi apparatus of alveolar type II cells and are stored in lamellar bodies until exocytosis (Fig. 1).Cited by: Pulmonary surfactant is a complex mixture of phospholipids and proteins that functions to reduce surface tension at the alveolar air interface preventing atelectasis.
Deficiency of pulmonary surfactant is the principal cause of respiratory distress syndrome in premature infants (Whitsett and Weaver, ). Surfactant therapy in combination with nasal continuous positive airway pressure (CPAP) has been shown to be superior to nasal CPAP alone in a small study of neonates with RDS.
Natural human pulmonary surfactant is secreted by the lamellar bodies of alveolar type-II cells, and is first synthesized in the fetus after 24—28 weeks of gestation. Lung surfactants are made from animal lung extract and contain phospholipids. Natural surfactant is produced by the alveolar cells in the lungs and line mainly the alveoli and small bronchioles, and prevents the alveoli from collapsing.
Lung surfactant makes it easier for oxygen to penetrate the lung surface lining and move into the blood. Book Description. This book represents a comprehensive update on pulmonary surfactant by merging classical knowledge with new information.
Topics include surfactant secretion and alveolar processing and recycling; physical bases and different theoretical models of the physiological mechanism for pulmonary surfactant action; recent findings on surfactant-like.
As described earlier, surfactant helps in reducing surface tension and thereby increases compliance of the lung. An absence of the surfactant leads to a decrease in pulmonary compliance, and this condition is called Newborn respiratory distress syndrome.
It is fatal and requires aggressive measures by continuous positive pressure breathing. Pulmonary surfactant is a lipoprotein complex responsible for preventing the collapse of alveoli and increasing lung compliance.Therapeutically, exogenous surfactant administration, or surfactant replacement therapy(SRT), is considered in preterm infants with radiographic (small volume lungs, haziness/ ground-glass appearance, air bronchograms and loss of cardiac.
Summary Pulmonary surfactant is a complex mixture of specific lipids, proteins and carbohydrates, which is produced in the lungs by type II alveolar epithelial cells. The mixture is surface active and acts to decrease surface tension at the air–liquid interface of the by: 4.
Pulmonary surfactant is a lipoprotein complex responsible for preventing the collapse of alveoli and increasing lung compliance.Therapeutically, exogenous surfactant administration, or. Ideal for fellows and practicing pulmonologists who need an authoritative, comprehensive reference on all aspects of pulmonary medicine, Murray and Nadel’s Textbook of Respiratory Medicine offers the most definitive content on basic science, diagnosis, evaluation and treatment of the full spectrum of respiratory diseases.
Included with your print purchase is the Expert. Surfactant in Preterm Infants Introduction Pulmonary surfactant is a complex mixture of phospholipids and proteins that serves to reduce alveolar surface tension. It is formed by type II pneumocytes from about 20 weeks of gestation.
Surfactant creates a. This article starts with a brief account of the history of research on pulmonary surfactant. We will then discuss the morphological aspects and composition of the pulmonary surfactant system. We describe the hydrophilic surfactant proteins A and D and the hydrophobic surfactant proteins B and C, with focus on the crucial roles of these proteins in the dynamics, Cited by: 5.
Engelskirchen, S. The pseudo-binary pulmonary surfactant system. Current Opinion in Colloid & Interface Science () 6. Clements, J.A., et al. Pulmonary Surface Tension and the Mucus Lining of the lungs: Some Theoretical Considerations.
Journal of Applied Physiology () 7. The role of pulmonary surfactant is to reduce the surface tension in the lungs and to facilitate breathing. Surfactant replacement therapy (SRT) aims at.
Pulmonary surfactant is a complex mixture of phospholipids and proteins that creates a cohesive surface layer over the alveoli which reduces surface tension and maintains alveolar stability therefore preventing atelectasis. Surfactant deficiency is a recognized cause of respiratory distress syndrome in the preterm neonate.
Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease.
Manage neonatal respiratory distress syndrome (RDS), acute respiratory distress syndrome (ARDS), and acute lung injury more effectively!5/5(1).Discusses about pulmonary surfactant.
This book contains a discussion on the management of hyaline membrane disease, from both the experimental and clinical points of view.Synthesis and Assembly of Surfactant. The major components of pulmonary surfactant include phospholipids (∼80%), neutral lipids (mainly cholesterol, ∼10%), and the two hydrophobic peptides (1–2%) surfactant protein B (SP-B) and SP-C.
Type II epithelial cells synthesize and assemble the lipid and protein components into complexes that are stored as tightly packed Cited by: